control 22 Search Results


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Alpha Diagnostics antibody nkcc11-a
Antibody Nkcc11 A, supplied by Alpha Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Il 22 Plasmids Control Plasmid, supplied by Genechem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Entrust Sc Naturalyte Insect Control, supplied by Dow AgroSciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Mass Flow Controllers F 201cv500 Rgd 33 V, supplied by Bronkhorst High Tech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Qiagen 22-mer negative control inhibitor
22 Mer Negative Control Inhibitor, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Ribobio co microntm mimic negative control #22
Microntm Mimic Negative Control #22, supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Controlled Environment Chamber Sg2 22, supplied by Hoffman Manufacturing Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Ribobio co mir agomir negative control (scrambled 22 nt, mir-scr)
Intra-articular Injection (IAJ) <t>of</t> <t>miR-140</t> Attenuates OA Progression in Rats (A) Experimental layout for the in vivo experiments in rats. (B) Representative in vivo fluorescence image 24 h after IAJ of Cy5-labeled miR-140 <t>agomir</t> into the right hind knee and normal saline (NS) injection into the left hind knee. (C) Representative fluorescence micrographs of sagittal frozen sections of the medial femoral condyles 24 h after IAJ of NS into the left hind knee (top) and Cy5-labeled miR-140 agomir into the right hind knee (bottom; 100× scale bars, 200 μm; 400× scale bars, 50 μm). (D) Number of rears, as measured by behavioral testing, before and after IAJ of miR-Scr or miR-140 agomir. (E–K) Gross observation (E), pathological lesion score (F), representative sagittal micrographs of H&E (G), and Safranin O (H) staining (scale bars, 100 μm) and modified Mankin score (I), cartilage thickness (J), and chondrocyte number (K) of the medial femoral condyles before and after IAJ of miR-Scr or miR-140 agomir. ACLT + DMM, anterior cruciate ligament transection (ACLT) and destabilization of the medial meniscus (DMM). *p < 0.05, **p < 0.01, ***p < 0.001.
Mir Agomir Negative Control (Scrambled 22 Nt, Mir Scr), supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Ribobio co negative control mimic (nc) (microntm mimic negative control #22, standard, 2nmol)
Intra-articular Injection (IAJ) <t>of</t> <t>miR-140</t> Attenuates OA Progression in Rats (A) Experimental layout for the in vivo experiments in rats. (B) Representative in vivo fluorescence image 24 h after IAJ of Cy5-labeled miR-140 <t>agomir</t> into the right hind knee and normal saline (NS) injection into the left hind knee. (C) Representative fluorescence micrographs of sagittal frozen sections of the medial femoral condyles 24 h after IAJ of NS into the left hind knee (top) and Cy5-labeled miR-140 agomir into the right hind knee (bottom; 100× scale bars, 200 μm; 400× scale bars, 50 μm). (D) Number of rears, as measured by behavioral testing, before and after IAJ of miR-Scr or miR-140 agomir. (E–K) Gross observation (E), pathological lesion score (F), representative sagittal micrographs of H&E (G), and Safranin O (H) staining (scale bars, 100 μm) and modified Mankin score (I), cartilage thickness (J), and chondrocyte number (K) of the medial femoral condyles before and after IAJ of miR-Scr or miR-140 agomir. ACLT + DMM, anterior cruciate ligament transection (ACLT) and destabilization of the medial meniscus (DMM). *p < 0.05, **p < 0.01, ***p < 0.001.
Negative Control Mimic (Nc) (Microntm Mimic Negative Control #22, Standard, 2nmol), supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Ribobio co mimic negative control #22
Intra-articular Injection (IAJ) <t>of</t> <t>miR-140</t> Attenuates OA Progression in Rats (A) Experimental layout for the in vivo experiments in rats. (B) Representative in vivo fluorescence image 24 h after IAJ of Cy5-labeled miR-140 <t>agomir</t> into the right hind knee and normal saline (NS) injection into the left hind knee. (C) Representative fluorescence micrographs of sagittal frozen sections of the medial femoral condyles 24 h after IAJ of NS into the left hind knee (top) and Cy5-labeled miR-140 agomir into the right hind knee (bottom; 100× scale bars, 200 μm; 400× scale bars, 50 μm). (D) Number of rears, as measured by behavioral testing, before and after IAJ of miR-Scr or miR-140 agomir. (E–K) Gross observation (E), pathological lesion score (F), representative sagittal micrographs of H&E (G), and Safranin O (H) staining (scale bars, 100 μm) and modified Mankin score (I), cartilage thickness (J), and chondrocyte number (K) of the medial femoral condyles before and after IAJ of miR-Scr or miR-140 agomir. ACLT + DMM, anterior cruciate ligament transection (ACLT) and destabilization of the medial meniscus (DMM). *p < 0.05, **p < 0.01, ***p < 0.001.
Mimic Negative Control #22, supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioMimetic Therapeutics sealant 22 99 diaper control solution
Intra-articular Injection (IAJ) <t>of</t> <t>miR-140</t> Attenuates OA Progression in Rats (A) Experimental layout for the in vivo experiments in rats. (B) Representative in vivo fluorescence image 24 h after IAJ of Cy5-labeled miR-140 <t>agomir</t> into the right hind knee and normal saline (NS) injection into the left hind knee. (C) Representative fluorescence micrographs of sagittal frozen sections of the medial femoral condyles 24 h after IAJ of NS into the left hind knee (top) and Cy5-labeled miR-140 agomir into the right hind knee (bottom; 100× scale bars, 200 μm; 400× scale bars, 50 μm). (D) Number of rears, as measured by behavioral testing, before and after IAJ of miR-Scr or miR-140 agomir. (E–K) Gross observation (E), pathological lesion score (F), representative sagittal micrographs of H&E (G), and Safranin O (H) staining (scale bars, 100 μm) and modified Mankin score (I), cartilage thickness (J), and chondrocyte number (K) of the medial femoral condyles before and after IAJ of miR-Scr or miR-140 agomir. ACLT + DMM, anterior cruciate ligament transection (ACLT) and destabilization of the medial meniscus (DMM). *p < 0.05, **p < 0.01, ***p < 0.001.
Sealant 22 99 Diaper Control Solution, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Intra-articular Injection (IAJ) of miR-140 Attenuates OA Progression in Rats (A) Experimental layout for the in vivo experiments in rats. (B) Representative in vivo fluorescence image 24 h after IAJ of Cy5-labeled miR-140 agomir into the right hind knee and normal saline (NS) injection into the left hind knee. (C) Representative fluorescence micrographs of sagittal frozen sections of the medial femoral condyles 24 h after IAJ of NS into the left hind knee (top) and Cy5-labeled miR-140 agomir into the right hind knee (bottom; 100× scale bars, 200 μm; 400× scale bars, 50 μm). (D) Number of rears, as measured by behavioral testing, before and after IAJ of miR-Scr or miR-140 agomir. (E–K) Gross observation (E), pathological lesion score (F), representative sagittal micrographs of H&E (G), and Safranin O (H) staining (scale bars, 100 μm) and modified Mankin score (I), cartilage thickness (J), and chondrocyte number (K) of the medial femoral condyles before and after IAJ of miR-Scr or miR-140 agomir. ACLT + DMM, anterior cruciate ligament transection (ACLT) and destabilization of the medial meniscus (DMM). *p < 0.05, **p < 0.01, ***p < 0.001.

Journal: Molecular Therapy. Nucleic Acids

Article Title: miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence

doi: 10.1016/j.omtn.2019.10.032

Figure Lengend Snippet: Intra-articular Injection (IAJ) of miR-140 Attenuates OA Progression in Rats (A) Experimental layout for the in vivo experiments in rats. (B) Representative in vivo fluorescence image 24 h after IAJ of Cy5-labeled miR-140 agomir into the right hind knee and normal saline (NS) injection into the left hind knee. (C) Representative fluorescence micrographs of sagittal frozen sections of the medial femoral condyles 24 h after IAJ of NS into the left hind knee (top) and Cy5-labeled miR-140 agomir into the right hind knee (bottom; 100× scale bars, 200 μm; 400× scale bars, 50 μm). (D) Number of rears, as measured by behavioral testing, before and after IAJ of miR-Scr or miR-140 agomir. (E–K) Gross observation (E), pathological lesion score (F), representative sagittal micrographs of H&E (G), and Safranin O (H) staining (scale bars, 100 μm) and modified Mankin score (I), cartilage thickness (J), and chondrocyte number (K) of the medial femoral condyles before and after IAJ of miR-Scr or miR-140 agomir. ACLT + DMM, anterior cruciate ligament transection (ACLT) and destabilization of the medial meniscus (DMM). *p < 0.05, **p < 0.01, ***p < 0.001.

Article Snippet: The miR-140 agomir and miR agomir negative control (scrambled 22 nt, miR-Scr; RiboBio) solutions were prepared immediately before injection.

Techniques: Injection, In Vivo, Fluorescence, Labeling, Saline, Staining, Modification

Intra-articular Injection (IAJ) of miR-140 Retards Chondrocyte Senescence in Rats (A–D) Representative micrographs of immunohistochemical staining and immunopositive percentage of p16 INK4a (A), p21 (B), p53 (C), and γH2AX (D) in sagittal sections of the medial femoral condyles after IAJ of miR-Scr or miR-140 agomir (scale bars, 100 μm for p16 INK4a , p21, and p53; 50 μm for γH2AX). *p < 0.05, **p < 0.01, ***p < 0.001.

Journal: Molecular Therapy. Nucleic Acids

Article Title: miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence

doi: 10.1016/j.omtn.2019.10.032

Figure Lengend Snippet: Intra-articular Injection (IAJ) of miR-140 Retards Chondrocyte Senescence in Rats (A–D) Representative micrographs of immunohistochemical staining and immunopositive percentage of p16 INK4a (A), p21 (B), p53 (C), and γH2AX (D) in sagittal sections of the medial femoral condyles after IAJ of miR-Scr or miR-140 agomir (scale bars, 100 μm for p16 INK4a , p21, and p53; 50 μm for γH2AX). *p < 0.05, **p < 0.01, ***p < 0.001.

Article Snippet: The miR-140 agomir and miR agomir negative control (scrambled 22 nt, miR-Scr; RiboBio) solutions were prepared immediately before injection.

Techniques: Injection, Immunohistochemical staining, Staining